Signs Of Low Functioning Gallbladder

Signs Of Low Functioning Gallbladder – Bile is an important digestive fluid produced by the liver and stored in concentrated form in the gallbladder. Bile’s primary digestive responsibility is to emulsify fats and create fatty acids that are easily absorbed and used by the body. When the body has metabolic problems that lead to poor production and use of bile, it can lead to serious health disorders and gallbladder disease.

Unfortunately, the traditional medical system has no solution for slow bile production, also called “bile stasis.” They just watch and wait until the gallbladder is so full of stones that it needs to be removed. This process takes years and is completely preventable.

Signs Of Low Functioning Gallbladder

A review study in the British Medical Journal found that 50% of patients who had gallbladder surgery had no improvement in their digestive problems (1). This article discusses the functions of the gallbladder and the symptoms of gallbladder disease.

Physical Symptoms Of Gallbladder Issues

1) Fatty Acid Metabolism: Bile salts are essential for the emulsification of dietary fats into bioavailable fatty acids. Without proper production and use of bile, we will have trouble digesting fats and fat-soluble vitamins such as vitamin A, D, E, K.

2) Excretion of waste: The function of the liver is to metabolize and inactivate toxins, while the bile captures toxins and helps transport them through the digestive tract and eliminate them in the feces. Bile also helps stimulate the peristaltic action of the intestines, which pushes stool in and out of the body.

3) Kill bad microbes: The small intestine should not normally have many bacteria, in part due to the presence of bile salts (2). Salts are natural preservatives that reduce bacterial fermentation. Insufficient bile production can lead to increased bacterial fermentation and the development of small intestinal bacterial overgrowth (SIBO), Candida or parasite overgrowth.

4) Blood sugar metabolism: Bile is essential for breaking down fatty acids for good fat metabolism. Poor fat metabolism will lead to blood sugar instability (3, 4). In addition, biliary FXR and TGR5 receptors help regulate lipid (fat) and carbohydrate metabolism and the inflammatory response (5, 6). Bile acids then activate these receptors.

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These symptoms indicate that your gallbladder may not be working well. This does not necessarily mean you have gallbladder disease, but it would be a good idea to get it investigated.

You can have many, but rarely all. It is always recommended that you report these symptoms to your primary care physician or functional physician and have functional laboratory tests.

1) Nausea and Vomiting: Any disorder in the digestive tract can sometimes cause a feeling of nausea and vomiting. This is a common problem with poor bile motility.

2) Fatty/Greasy stools: Poor bile secretion results in ineffective emulsification of dietary fats and leads to excretion of undigested fat in the stool.

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3) Pain between the shoulder blades: the liver and gall bladder themselves do not feel pain, but the nerves that animate them also go to the back muscles. Especially the area just below the right shoulder blade.

4) Abdominal pain: When the liver and gallbladder become inflamed, it can cause bloating, distension and pain throughout the abdominal area. Sometimes the swelling makes the whole breast hurt or just “weird”.

5) Chronic Gas and Bloating: Insufficient bile production will lead to poor intestinal motility and microbial growth and fermentation. The fermentation process causes gas to form, which can cause bloating and cramping.

6) Itchy skin: This is also called itching. When the gallbladder becomes blocked, there is an increase in a compound called autotaxin (ATX) and lysophosphatidic acid (LPA), which causes the characteristic itching (7).

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7) Yellowing of the skin: Bilirubin is a yellow pigment and when the body cannot metabolize bilirubin effectively, it ends up seeping into the tissues near the skin. This is a condition called jaundice.

8) Headaches and Migraines: Gallbladder congestion can cause stress on the body and more intestinal inflammation. Both mechanisms can increase tension in the blood supply to the skull and brain and cause headaches and migraines.

9) Constipation and Diarrhea: Poor bile motility will slow the peristaltic action of the intestines, resulting in higher rates of constipation and frequent alternating episodes of diarrhea and constipation.

10) Light-colored stools: Bilirubin in bile helps create the classic darkening of stools. If you often notice lighter stools, this may be the result of poorly functioning bile ducts.

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11) Sexual Dysfunction: Slow bile function can cause a decrease in the overall balance of sex hormones as the liver metabolizes the steroid hormones estrogen, testosterone and progesterone. As a result, the person may have problems with menstrual function, sexual function and fertility.

13) Fibromyalgia: This chronic pain condition is usually due in part to low hydrochloric acid and an underactive liver and gallbladder.

14) Hypothyroidism: People with hypothyroidism often have an underactive biliary system. It’s hard to say which comes first, but they flow into each other.

15) Loss of hunger: Feeling full all the time is often a sign of a sluggish digestive system, which includes bile stasis.

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16) Dry skin and hair: Malabsorption of fatty acids will result in poor utilization of fatty acids and deficiency of fat-soluble vitamins (A, E, D and K). This can lead to dry, flaky skin and thin, dry hair, among other problems.

17) Chemical sensitivity: People who have an increased reaction to chemicals often suffer from an underactive liver and biliary system.

18) History of prescription, non-prescription or illegal drug use: All of these can put undue strain on the liver and overload it, leading to bile stasis.

19) Resistance to weight loss: If we can’t metabolize fatty acids well, we won’t be able to use the calories they provide, leading to unstable blood glucose. Blood sugar instability will cause hormonal changes that will cause resistance to weight loss.

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20) Rashes: Slow bile causes leaky gut syndrome. When the gut is affected, it releases substance P, which, when increased in the bloodstream, can cause rashes and eczema on the skin.

22) IT Band Pain: The iliotibial (IT) band runs from the side of the hip to the side of the knee. This band can often be very tight and painful in people with gallbladder dysfunction.

In addition, stagnant bile can lead to microbial overgrowth and infection, causing gallbladder disease. If the gallbladder becomes infected, you may experience pain in your right side and a fever. Many of these symptoms can be confused with other diseases, such as kidney stones, heart attack and hepatitis. If you have these symptoms, you should consider gallbladder disease and rule out other conditions.

Sources for this article include: 1. Bateson MC. Gallbladder disease. BMJ: British Medical Journal. 1999;318(7200):1745-1748. 2. Hofmann AF, Eckmann L. How bile acids protect the intestinal mucosa from bacteria. Proceedings of the National Academy of Sciences of the United States of America. 2006? 103(12): 4333-4334. 3. Wei J, Qiu de K, Ma X. Bile acids and insulin resistance: implications for the treatment of nonalcoholic fatty liver disease. J Dig Dis. May 2009; 10(2): 85-90. PMID: 19426389 4. Hylemon PB, Zhou H, Pandak WM, Ren S, Gil G, Dent P. Bile acids as regulatory molecules. J Lipid Res. 2009 Aug;50(8):1509-20. PMID: 19346331 5. Fuchs M. Non-alcoholic fatty liver disease: the bile acid-activated farnesoid X receptor as an emerging therapeutic target. Lipid Journal. 2012? 2012: 934396. 6. Li Y, Jadhav K, Zhang Y. Bile acid receptors in nonalcoholic fatty liver disease. Biochem Pharmacol. December 1, 2013; 86(11): 1517-24. PMID: 23988487 7. Serum autotaxin is elevated in pruritus of cholestasis, but not of other origin and responds to therapeutic interventions Link here

Liver And Gallbladder: Signs, Symptoms, And Treatment

“Join my tribe today to discover hidden strategies to improve your energy, brain, digestion and metabolism.” — Dr. David Jokers. A functional gallbladder disorder is a gallbladder motility disorder that causes reduced gallbladder contractility and colic pain. The term is used to capture the constellation of symptoms that led to its coding in the Rome III criteria (Table 1).

Previously, the functional disorder of the gallbladder was called chronic asthmatic cholecystitis, chain cholecystitis, biliary dyskinesia or biliary dysmotility. It is usually diagnosed in the office, which has led to an increase in the number of cholecystectomies performed for functional gallbladder disorders over the past two decades, from an initial incidence of 5% to between 20% and 25%.

Functional gallbladder disorder should be a diagnostic test in any patient with classic biliary symptoms and normal right upper quadrant ultrasound findings and normal liver and pancreatic enzyme levels.

It must include episodes of epigastric and/or right upper quadrant pain and all of the following:

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Pain is moderate to severe enough to interrupt the patient’s daily activities or prompt a visit to the emergency department

Etiologically, there appears to be a link between gallbladder dysfunction and obesity. Several studies have shown that obesity causes fatty infiltration of internal organs and causes chronic inflammation.

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